Christoforidis Th. Medicine Unit, Companion Animals Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki
Sevastoudi St. Medicine Unit, Companion Animals Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki
Karafylia An. Medicine Unit, Companion Animals Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki
Kontidis D. Medicine Unit, Companion Animals Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki
Farmaki R. Medicine Unit, Companion Animals Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki
Patsikas M. Laboratory of Diagnostic Imaging, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki
Soubasis N. Medicine Unit, Companion Animals Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki
Introduction
Hypercoagulability is considered a possible complication in dogs with hyperadrenocorticism. The aim of this study is to present a rare case of subclavian arterial thrombosis associated with hyperadrenocorticism in a dog.
Clinical Case
A 15-year-old female Maltese dog was presented with a three-month-history of polyuria/polydipsia and an acute onset of non-weight-bearing lameness in the right forelimb. On physical examination, generalized non-pruritic symmetrical hypotrichosis/ alopecia and extreme pain of the forearm were observed. Serum biochemistry showed an elevation in liver enzymes. A damage of the lower motor neurons of the right forelimb was revealed in neurological examination. Computed tomography-angiography demonstrated a thrombus in the right subclavian artery and enlargement of both adrenal glands. Antithrombotic and antiplatelet treatment was administered.
Results
In the clinical examination, 3 weeks later, the dog showed considerable improvement in ambulatory function. A low dose dexamethasone suppression test was performed which was compatible with hyperadrenocorticism. The owner refused treatment with trilostane and the dog continued the antithrombotic treatment indefinitely.
Conclusions
Dogs with hyperadrenocorticism might develop serious and threatening secondary complications. Although it has been documented in literature, hypercoagulability in hyperadrenocorticism needs to be further researched in order for the clinician to be able to manage such cases.
References
- Eom T-Y, Choi J-W, Yoon K-A, Jeong S-W and Kim J-H (2021) Case Report: Non-traumatic Unilateral Forelimb Thrombosis Associated With Hyperadrenocorticism in a Dog. Front. Vet. Sci. 8:795928. doi: 10.33389/fvets.2021.795928.
- Yang VK, Cunningham SM, Rush JE, de Laforcade A (2016) The use of rivaroxaban for the treatment of thrombotic complications in four dogs. J Vet Emerg Crit Care 26, 729-7363. doi: 10.111/vec.12466.
- deLaforcade A, Bacek L, Blais MC, Goggs R, Lynch A, Rozanski E. Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 1-Defining populations at risk. J Vet Emerg Crit Care (2019) 29,3. doi: 10.1111/vec.12797.
